IEN - Biocleanroom
Soft Materials and Bio-Technologies Applications

Bioanalysis Applications

Biacore T200 

  • Increase understanding of molecular mechanisms and structure-function relationships
  • Select, characterize, and assess comparability of biotherapeutics
  • Select and optimize lead compounds during drug discovery
  • Detect and characterize antidrug antibodies (ADA) in immunogenicity studies
  • Perform time- and cost-efficient concentration analysis

 

 Q-sense QCM-D

Study surface interactions:

  • In real-time
  • With nanogram precision

 

Analyze events such as:

  • Adsorption/Desorption
  • Binding
  • Degradation
  • Cross-linking
  • Swelling/Collapse

 

Find out:

  • How much?
  • How fast?
  • What process?
  • What structure?

 

Particle Size and Zeta Potential Applications             

Malvern Zetasizer                                                                               

  • Shorten development time for emulsions and dispersion of nanoparticles, liposomes, colloids and protein and polymer formulations.
  • Assess and improve protein formulation stability and improve shelf life
  • Investigate zeta potential of surfaces
  • Explore protein aggregation and oligomeric state
  • Surfactant micelle characterisation using dynamic light scattering
  • Improve ink, toner and pigment performance
  • Optimise flocculant dosage to reduce cost for water treatment

 

Goniometry Applications

Ramé-hart Model 250 Contact Angle

Useful for measuring the following:

  • contact angle
  • surface energy, surface and interfacial tension
  • surface dilatational elasticity and viscosity
  • advancing and receding contact angles
  • roll off angle
  • contact angle hysteresis.
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Contact Information
Linda Tian
Biocleanroom Engineer
ltian31@gatech.edu
(470) 543-0545